Methylprednisolone
Solu-Medrol
Class:
Corticosteroid. Related to Solu-Cortef.
Corticosteroid. Related to Solu-Cortef.
Mechanism of Action:
- Supresses acute and chronic inflammation.
- Replaces absent glucocortocoids.
- Immunosuppressive effects.
Indications:
- Asthma
- Anaphylaxis
- Croup
- Adrenal insufficiency
Contraindications:
Hypersensitivity to product.
Hypersensitivity to product.
Adverse reactions:
- Hypertension, sodium and water retetion, GI bleeding, TB.
- None from single dose.
Drug Interactions
Calcium
Calcium
Adult Dosage and Administration
125mg IV bolus.
125mg IV bolus.
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Pediatric Dosage and Administration:2 mg/kg IV bolus to maximum of 125mg.
Duration of Action
- Onset: Minutes to Hours (depending on indication).
- Peak effect: 8-12 hours.
Special Considerations:
- Protect medication from heat.
- Toxicity and side effects with long-term use.